Article

Hepatic and Brain Spatial Gene Expression Changes in Intragastric Alcohol Fed APP/PS1 Alzheimer's Disease Mouse Model

2026-08-24

Abstract excerpt

<title>Abstract</title> Background Alcohol use is increasingly recognized as a significant modifier of Alzheimer's disease (AD) risk and progression. Two key organs, the liver and the brain, are central to understanding the impact of alcohol intake on AD. This is due to the liver being the primary site of alcohol detoxification and a major target of alcohol-induced injury, while the brain harbors the neurop...

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Literature Corpus work: df190571-9bf3-5e78-b71b-40accf9c7dec
DOI: 10.21203/rs.3.rs-10760512/v1

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