Article
Alcohol Drinking Exacerbates Neural and Behavioral Pathology in the 3xTg-AD Mouse Model of Alzheimer’s Disease
2019-08-06
Abstract excerpt
<h4>ABSTRACT</h4> Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that represents the most common cause of dementia in the United States. Although the link between alcohol use and AD has been studied, preclinical research has potential to elucidate neurobiological mechanisms that underlie this interaction. This study was designed to test the hypothesis that non-dependent alcohol drinking exac...
Topics
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- Adipose Tissue and Metabolism
- Advanced Proteomics Techniques and Applications
- Alzheimer's disease research and treatments
- Cholinesterase and Neurodegenerative Diseases
- Computational Drug Discovery Methods
- Neuroinflammation and Neurodegeneration Mechanisms
- Nuclear Receptors and Signaling
- S100 Proteins and Annexins
Identifiers and source
- Literature Corpus work
- 97a57c1a-4f0d-5fcb-880b-0040cfad86ec
- DOI
- 10.1101/726307
