Back to search

Article

Impaired Pathways of Detoxification and Risk of Alzheimer’s Disease in Humans - Differential Gene Expression Studies via Gene Set Expression Analysis

2025-05-31

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Alzheimer’s disease (AD) is an all-too-common dementing disease associated with aging, impacting individuals, their families, and society. No specific etiology has been determined despite extensive research over the last century. <h4>Objective</h4> Detoxification is a multifaceted systemic process of variable efficacy that eliminates potentially hazardous exogenous and endogen...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
34c59589-d7b5-58ca-9c13-8e6e3f2546b3
DOI
10.1101/2025.05.29.25328282
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Impaired Pathways of Detoxification and Risk of Alzheimer’s Disease in Humans - Differential Gene Expression Studies via Gene Set Expression AnalysisDOI 10.1101/2025.05.29.25328282
A Map of Transcriptomic Signatures of Different Brain Areas in Alzheimer’s DiseaseSemantic proximity
Identification of disulfidptosis-related genes and subgroups in Alzheimer’s diseaseSemantic proximity
Identification of lipid metabolism-related genes and their roles in Alzheimer’s disease: a multi-omics analysisSemantic proximity
Machine learning identification and immune infiltration of disulfidptosis‐related Alzheimer's disease molecular subtypesSemantic proximity
Identification of chemicals targeting dementia genes and pathways in the Comparative Toxicogenomics DatabaseSemantic proximity
Transcriptional Alterations Related to Neuropathology and Clinical Manifestation of Alzheimer’s DiseaseSemantic proximity
Systematic analysis to identify transcriptome-wide dysregulation of Alzheimer's disease in genes and isoforms.Semantic proximity
Bioinformatics to analyze the differentially expressed genes in different degrees of Alzheimer’s disease and their roles in progress of the diseaseSemantic proximity
Integrative Transcriptomic Analysis Identifies Conserved Molecular Signatures and Drug Repurposing Candidates in Alzheimer’s DiseaseSemantic proximity
Sporadic Alzheimer disease fibroblasts display an oxidative stress phenotype.Semantic proximity
Unveiling disulfidptosis-related biomarkers and predicting drugs in Alzheimer’s diseaseSemantic proximity
Data-Driven Analysis of Age, Sex, and Tissue Effects on Gene Expression Variability in Alzheimer’s DiseaseSemantic proximity
Select a neighboring publication to make it the new centre.