Article

Ethanol exposure alters Alzheimer’s-related pathology, behavior, and metabolism in APP/PS1 mice

2022-02-20

Abstract excerpt

Chronic ethanol exposure can increase amyloid-β (Aβ) and tau in rodent models of Alzheimer’s-disease (AD)-like pathology, yet the underlying mechanisms are poorly understood. In this study, a moderate two-bottle choice drinking paradigm was used to identify how chronic ethanol exposure alters Aβ-related pathology, metabolism, and behavior. Complementary in vivo microdialysis experiments were used to measure how ac...

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Literature Corpus work: 2d839b0f-86c5-591a-867e-ae8763621577
DOI: 10.1101/2022.02.18.481066

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