Article

Insights into polyprotein processing and RNA-protein interactions in foot-and-mouth disease virus genome replication

2023-01-26

Abstract excerpt

Foot-and-mouth disease affects cloven hoofed animals and is caused by foot-and-mouth disease virus (FMDV), a picornavirus with a positive-sense RNA genome. The FMDV genome contains a single open reading frame, which is translated to produce a polyprotein that is cleaved by viral proteases to produce the viral structural and non-structural proteins. Initial processing of the polyprotein occurs at three main junctio...

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Literature Corpus work: 6f4fcf61-89ae-54f2-a3c9-1013f63624b5
DOI: 10.1101/2023.01.26.525530

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