Article
Hepatitis G virus encodes protease activities which can effect processing of the virus putative nonstructural proteins.
Journal of virology - 1 Jan 1998
Belyaev A S, Chong S, Novikov A, Kongpachith A, Masiarz F R, Lim M, Kim J P
Abstract excerpt
The genome of a recently identified virus, hepatitis G virus (HGV), shows considerable homology to hepatitis C virus (HCV). Two HGV proteases similar to nonstructural proteins NS2 and NS3 of HCV were identified, and their cleavage site specificity was investigated. Amino acids essential for the p...
Topics
- Amino Acid Sequence
- Baculoviridae
- Binding Sites
- Endopeptidases
- Flaviviridae
- Humans
- Molecular Sequence Data
- Mutation
- Oligodeoxyribonucleotides
- Protein Processing, Post-Translational
- Recombinant Proteins
- Viral Nonstructural Proteins