Article

Two-Stage CD8 <sup>+</sup> CAR T-Cell Differentiation in Patients with Large B-Cell Lymphoma

2025-03-11

Abstract excerpt

<h4>SUMMARY</h4> Chimeric antigen receptor (CAR) T-cell therapy has expanded therapeutic options for patients with diffuse large B-cell lymphoma (DLBCL). However, progress in improving clinical outcomes has been limited by an incomplete understanding of CAR T-cell differentiation in patients. To comprehensively investigate CAR T-cell differentiation in vivo, we performed single-cell, multi-modal, and longitudinal...

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Literature Corpus work: deaddf63-2d42-5ff9-8699-2725be640237
DOI: 10.1101/2025.03.05.641715

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