Article

Genetic and phenotypic architecture of human myocardial trabeculation

2024-03-27

Abstract excerpt

Cardiac trabeculae form a network of muscular strands that line the inner surfaces of the heart. Their development depends on multiscale morphogenetic processes and, while highly conserved across vertebrate evolution, their role in the pathophysiology of the mature heart is not fully understood. We report variant associations across the allele frequency spectrum for trabecular morphology in 47,803 participants of...

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Literature Corpus work: 39f9d33b-79c5-5a94-bd93-15fa264622dc
DOI: 10.1101/2024.03.26.24304726

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