Article

Antibodies Expand the Scope of Angiotensin Receptor Pharmacology

2023-08-24

Abstract excerpt

G protein-coupled receptors (GPCRs) are key regulators of human physiology and are the targets of many small molecule research compounds and therapeutic drugs. While most of these ligands bind to their target GPCR with high affinity, selectivity is often limited at the receptor, tissue, and cellular level. Antibodies have the potential to address these limitations but their properties as GPCR ligands remain poorly...

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Literature Corpus work: de4b6377-f7fd-58be-996a-ae275a06fe9d
DOI: 10.1101/2023.08.23.554128

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