Article

Precision Aptamers Against a Native GPCR through Ligand-Guided Selection

2026-05-07

Abstract excerpt

G protein–coupled receptors (GPCRs) constitute the largest and most diverse class of membrane receptors encoded in the human genome. They detect a wide range of chemical and physical stimuli and transduce these signals into intracellular responses through highly regulated pathways. Reflecting their central role in physiology, GPCRs are among the most prominent targets in drug discovery. However, identifying ligand...

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Literature Corpus work: 8d698584-82f3-5b54-b751-6c7041fa7e45
DOI: 10.64898/2026.05.04.722743

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