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Article

Exploring type I angiotensin (AT<sub>1</sub>) receptor functions through gene targeting

29 Jul 2004

Abstract excerpt

The renin-angiotensin system (RAS) modulates a diverse set of physiological processes including development, blood pressure, renal function and inflammation. The principal effector molecule of this system, angiotensin II, mediates most of these actions. The classically recognized functions of the RAS are triggered via the type 1 (AT(1)) class of angiotensin receptors. Pharmacological blockade of the AT(1)...

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PMID: 15283771
DOI: 10.1111/j.1365-201x.2004.01331.x

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