Article

A Multi-Polygenic Risk Score Approach Incorporating Physical Activity Genotypes for Predicting Type 2 Diabetes and Associated Comorbidities: A FinnGen Study

2025-10-01

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Aims/hypothesis</h4> Genetic prediction of type 2 diabetes risk has proven difficult using current methods. Recent studies have shown that genetic variants associated with physical activity behavior are linked to type 2 diabetes incidence. This study investigated how a polygenic risk score (PRS) for type 2 diabetes relates to the incidence of type 2 diabetes and its comorbidities and whethe...

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Literature Corpus work: de1b49ab-82bb-513a-86eb-8afd5c97213a
DOI: 10.1101/2025.09.30.25336952

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