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Article

HBV DNA is a substrate for the cGAS/STING pathway but is not sensed in infected hepatocytes

2019-12-06

Abstract excerpt

HBV chronic infection is a critical risk factor for hepatocellular carcinoma. Although debated, the absence of innate immune response to HBV infection in hepatocytes is becoming the current view. However the underlying reasons are poorly understood. This study aims to define potential viral pathogen-associated molecular patterns (PAMPs) and the pattern recognition receptors (PRRs), and to elucidate whether HBV cou...

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Literature Corpus work
ddfe5b5e-f306-522f-9451-77ccfc9c94a5
DOI
10.1101/867440
Open publication

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HBV DNA is a substrate for the cGAS/STING pathway but is not sensed in infected hepatocytesDOI 10.1101/867440
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