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Regulation of Pattern-Recognition Receptor Signaling by HBX During Hepatitis B Virus Infection

17 Feb 2022

Abstract excerpt

As a small DNA virus, hepatitis B virus (HBV) plays a pivotal role in the development of various liver diseases, including hepatitis, cirrhosis, and liver cancer. Among the molecules encoded by this virus, the HBV X protein (HBX) is a viral transactivator that plays a vital role in HBV replication and virus-associated diseases. Accumulating evidence so far indicates that pattern recognition receptors (PRRs) are...

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PMID: 35251017
DOI: 10.3389/fimmu.2022.829923

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