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Hepatitis B Virus Can Be Sensed by STING-dependent DNA Sensors but Suppresses the DNA Sensing Pathway in Humans with Acute and Chronic Hepatitis B Virus Infection

2020-02-12

Abstract excerpt

<title>Abstract</title> <p>Background : With the discovery of stimulator of interferon genes (STING) in 2008, many intracellular molecules have been identified as STING-dependent DNA sensors in recent years. Studies show the DNA sensor-STING-IFN-β pathway plays an important role in defense against viral infections. However, the recognition of hepatitis B virus (HBV) by DNA sensors is still largely unclear. In thi...

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Literature Corpus work
256aa731-64a7-58c5-a20c-51ce77152638
DOI
10.21203/rs.2.23304/v1
Open publication

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Hepatitis B Virus Can Be Sensed by STING-dependent DNA Sensors but Suppresses the DNA Sensing Pathway in Humans with Acute and Chronic Hepatitis B Virus InfectionDOI 10.21203/rs.2.23304/v1
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