Article

STING Mediates Cytosolic Dna-Induced Muc5ac Mrna Expression in Human Bronchial Epithelial Cells

2020-06-29

Abstract excerpt

<title>Abstract</title> <p><bold>Background</bold>: Non-autologous and autologous cytosolic DNA are recognized as danger signals by cytoplasmic sensor molecules that activate signal-transduction pathways. An important molecule in cytosolic DNA sensing is stimulator of interferon genes (STING), an endoplasmic reticulum protein activated by cyclic GMP–AMP (cGAMP) produced in response to cytosolic DNA. STING is impo...

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Literature Corpus work: 57d8dc08-9d30-5da2-bd4d-42048fd28925
DOI: 10.21203/rs.3.rs-37814/v1

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