Article

Progerin-Induced Nuclear Envelope Remodeling is Shaped by Cell Division and NUP153

2026-01-26

Abstract excerpt

<h4>ABSTRACT</h4> The nuclear envelope (NE) undergoes dynamic remodeling during both physiological and pathological processes. Nuclei in cells from patients with accelerated aging diseases and from elder individuals are often lobular and convoluted. Despite extensive study, the steps of phenotype acquisition and the co-factors required are not yet fully understood. Here, we focused on progerin, a mutant form of l...

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Literature Corpus work: ddd0ec39-fae7-53b9-b11d-84ed7c7b12c2
DOI: 10.64898/2026.01.23.701344

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