Article

Multi-Region Brain Organoid –Fusion Organoid with Cerebral, Endothelial and Mid-Hindbrain Components

2025-01-21

Abstract excerpt

Brain organoid technology has revolutionized our ability to model human neurodevelopment in vitro. However, current techniques remain limited by their reliance on simplified endothelial cell populations rather than a complete endothelial system. We engineered Multi-Region Brain Organoids (MRBOs) that integrate cerebral, mid/hindbrain, and complex endothelial organoids into one structure. Different from the earlier...

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Literature Corpus work: 5b2fb59a-1ac7-584c-96fa-271b4c0d1161
DOI: 10.1101/2025.01.20.633788

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