Article

An InDel Genomic Variant within a Bifunctional Super-Enhancer for LINC00636 and CD47 Regulation in Breast Cancer

2026-05-12

Abstract excerpt

<title>Abstract</title> <p>Highly accessible genomic super-enhancers often drive tumor-promoting programs, yet the impact of genomic variation within these regulatory elements remains unclear. Here, we identified a bifunctional super-enhancer that regulates the expression of cancer-promoting genes LINC00636 and CD47 in breast cancer. We discovered that a common germline insertion variant within the super-enhancer...

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Literature Corpus work: dd726535-6269-5da3-8a1f-febe8a7cb70e
DOI: 10.21203/rs.3.rs-9460487/v1

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