Article

Clonal Expansion of Alveolar Fibroblast Progeny Drives Pulmonary Fibrosis

2025-06-03

Abstract excerpt

<h4>ABSTRACT</h4> Pulmonary fibrosis has been called a fibroproliferative disease but the functional importance of proliferating fibroblasts to pulmonary fibrosis has not been systematically examined. In response to alveolar injury, resting alveolar fibroblasts differentiate into fibrotic fibroblasts that express high levels of collagens. However, what role, if any, proliferation plays in the accumulation of fibr...

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Literature Corpus work: dd701bef-89ad-5d3c-95c0-c73337bac06f
DOI: 10.1101/2025.05.31.657194

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