Article

NGFR as a biomarker and actionable target in cisplatin-based chemoradiotherapy–resistant HNSCC

2025-12-29

Abstract excerpt

Head and neck squamous cell carcinoma (HNSCC) is an aggressive malignancy with high mortality rates, often exhibiting resistance to conventional treatments such as radiotherapy (RT) or a combination of chemotherapy and radiotherapy (CRT). The nerve growth factor receptor (NGFR, also known as p75NTR or CD271) is a well-established cancer stem cell marker in melanoma, where it has been linked to resistance to multip...

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Literature Corpus work: dd65ff2c-7095-511e-86c2-981acf3d0939
DOI: 10.64898/2025.12.25.25342978

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