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Article

Identification of cisplatin-resistance related genes in head and neck squamous cell carcinoma.

International journal of cancer - 15 Jan 2010

Yamano Yukio, Uzawa Katsuhiro, Saito Kengo, Nakashima Dai, Kasamatsu Atsushi, Koike Hirofumi, Kouzu Yukinao, Shinozuka Keiji, Nakatani Ken, Negoro Kenji, Fujita Shigeyuki, Tanzawa Hideki

Abstract excerpt

Resistance to cisplatin is a major obstacle to successful treatment of head and neck squamous cell carcinoma (HNSCC). To investigate the molecular mechanism of this resistance, we compared the gene expression profiles between the cisplatin-sensitive SCC cell lines (Sa-3, H-1 and KB) and the cisplatin-resistant cell lines established from them (Sa-3R, H-1R and KB-R) using Affymetrix U133 Plus 2.0 microarray. We...

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Identifiers

PMID: 19569180
DOI: 10.1002/ijc.24704

Genes

LUM
NRG1
PKD2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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