Article

Tracking of Melanoma Cell Plasticity by Transcriptional Reporters

2022-01-13

Abstract excerpt

Clonal evolution and cellular plasticity are the genetic and non-genetic driving forces of tumor heterogeneity that in turn determines the tumor cell response towards therapeutic drugs. Several lines of evidence suggest that therapeutic interventions foster the selection of drug resistant neural crest stem-like cells (NCSCs) that establish minimal residual disease (MRD) in melanoma. Here we established a dual repo...

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Literature Corpus work: 2792f9cf-eee8-5dca-968a-69d2e0dc3d13
DOI: 10.20944/preprints202112.0373.v2

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