Article
Radiation resistance in head and neck squamous cell carcinoma: dire need for an appropriate sensitizer
10 Mar 2020
Abstract excerpt
Radiation is a significant treatment for patients with head and neck cancer. Despite advances to improve treatment, many tumors acquire radiation resistance resulting in poor survival. Radiation kills cancer cells by inducing DNA double-strand breaks. Therefore, radiation resistance is enhanced by efficient repair of damaged DNA. Head and neck cancers overexpress EGFR and have a high frequency of p53 mutations,...
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