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Does <i>Borrelia afzelii</i> outer surface protein E coevolve with complement factor H of its rodent host? Insights from GxG and spatial associations

2026-07-11

Abstract excerpt

<h4>Background</h4> Lyme borreliosis is a common tick-borne disease in Europe caused by spirochetes of the Borrelia burgdorferi sensu lato complex, including Borrelia afzelii , which is maintained in nature through interactions with rodent reservoir hosts. These spirochetes have evolved several surface proteins to manipulate rodent host immunity, some of which remain polymorphic in Borrelia populations. Among...

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Literature Corpus work: dd550c81-bae0-58e2-8c5d-be9b63c69745
DOI: 10.64898/2026.07.10.737716

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