Article

Structural evolution of an immune evasion determinant shapes Lyme borreliae host tropism

2022-09-14

Abstract excerpt

<h4>ABSTRACT</h4> The preferential adaptation of pathogens to specific hosts, known as host tropism, evolves through host-pathogen interactions. Transmitted by ticks and maintained primarily in rodents and birds, the Lyme disease-causing bacterium Borrelia burgdorferi ( Bb ) is an ideal model to investigate the mechanisms of host tropism. In order to survive in hosts and escape complement-mediated clearance, a...

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Literature Corpus work: 1a6ef875-eb11-5053-818c-a4c7e7c81be3
DOI: 10.1101/2022.09.13.507797

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