Article
Interplay between vertebrate adaptive immunity and bacterial infectivity genes: Bank vole MHC versus Borrelia afzelii OspC.
Molecular ecology - 1 Nov 2024
Różańska-Wróbel Joanna, Migalska Magdalena, Urbanowicz Anna, Grzybek Maciej, Rego Ryan O M, Bajer Anna, Dwuznik-Szarek Dorota, Alsarraf Mohammed, Behnke-Borowczyk Jolanta, Behnke Jerzy M, Radwan Jacek
Abstract excerpt
Coevolution of parasites with their hosts may lead to balancing selection on genes involved in determining the specificity of host-parasite interactions, but examples of such specific interactions in wild vertebrates are scarce. Here, we investigated whether the polymorphic outer surface protein C (OspC), used by the Lyme disease agent, Borrelia afzelii, to manipulate vertebrate host innate immunity, interacts...
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