Article

Phylogenomic diversity elucidates mechanistic insights into Lyme borreliae host association

2022-05-25

Abstract excerpt

<h4>ABSTRACT</h4> Host association– the selective adaptation of pathogens to specific host species – evolves through constant interactions between host and pathogens, leaving a lot yet to be discovered on immunological mechanisms and genomic determinants. The causative agents of Lyme disease (LD) are spirochete bacteria composed of multiple species of the Borrelia burgdorferi sensu lato complex, including B. bu...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 574b297c-fc3f-5aac-b058-26c415efd786
DOI: 10.1101/2022.05.25.493352

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Phylogenomic diversity elucidates mechanistic insights into Lyme borreliae host associationDOI 10.1101/2022.05.25.493352Read

Host tropism determination by convergent evolution of immunological evasion in the Lyme disease systemSemantic proximity Read

Structural evolution of an immune evasion determinant shapes Lyme borreliae host tropismSemantic proximity Read

Host tropism determination by convergent evolution of immunological evasion in the Lyme disease systemSemantic proximity Read

Structural evolution of an immune evasion determinant shapes pathogen host tropismSemantic proximity Read

Host specialization in microparasites transmitted by generalist vectors: insights into the cellular and immunological mechanismsSemantic proximity Read

Cellular and immunological mechanisms influence host-adapted phenotypes in a vector-borne microparasite.Semantic proximity Read

Outer surface protein polymorphisms linked to host‐spirochete association in Lyme borreliaeSemantic proximity Read

Host adaptation drives genetic diversity in a vector-borne disease systemSemantic proximity Read

Fast, adaptive evolution at a bacterial host-resistance locus: the PFam54 gene array in Borrelia burgdorferi.Semantic proximity Read

Lyme Disease PathogenesisSemantic proximity Read

Host adaptation drives genetic diversity in a vector-borne disease systemSemantic proximity Read

Host adaptation drives genome evolution and virulence diversification in a bacterial zoonotic pathogenSemantic proximity Read