Article
Dzip1 and Fam92 form a ciliary transition zone complex with cell type specific roles in Drosophila.
eLife - 10 Dec 2019
Lapart Jean-André, Gottardo Marco, Cortier Elisabeth, Duteyrat Jean-Luc, Augière Céline, Mangé Alain, Jerber Julie, Solassol Jérôme, Gopalakrishnan Jay, Thomas Joëlle, Durand Bénédicte
Abstract excerpt
Cilia and flagella are conserved eukaryotic organelles essential for cellular signaling and motility. Cilia dysfunctions cause life-threatening ciliopathies, many of which are due to defects in the transition zone (TZ), a complex structure of the ciliary base. Therefore, understanding TZ assembly, which relies on ordered interactions of multiprotein modules, is of critical importance. Here, we show that...
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