Article
The class I PITP giotto is required for Drosophila cytokinesis.
Current biology : CB - 24 Jan 2006
Giansanti Maria Grazia, Bonaccorsi Silvia, Kurek Roman, Farkas Rebecca M, Dimitri Patrizio, Fuller Margaret T, Gatti Maurizio
Abstract excerpt
Phosphatidylinositol transfer proteins (PITPs) are highly conserved polypeptides that bind phosphatidylinositol or phosphatidylcholine monomers, facilitating their transfer from one membrane compartment to another . Although PITPs have been implicated in a variety of cellular functions, including lipid-mediated signaling and membrane trafficking, the precise biological roles of most PITPs remain to be elucidated...
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