Article

Ciliary transition zone proteins coordinate ciliary protein composition and ectosome shedding

2021-12-08

Abstract excerpt

<title>Abstract</title> <p>The transition zone (TZ) of the cilium/flagellum serves as a diffusion barrier that controls the entry/exit of ciliary proteins. Mutations of the TZ proteins disrupt barrier function and lead to multiple human diseases. However, the systematic regulation of ciliary composition and signaling-related processes by different TZ proteins is not completely understood. Here, we reveal that los...

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Literature Corpus work: c03f7e94-c825-5258-acbe-0275d8073012
DOI: 10.21203/rs.3.rs-1142196/v1

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