Article

Strong spurious transcription likely a cause of DNA insert bias in typical metagenomic clone libraries

2015-01-15

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Clone libraries provide researchers with a powerful resource with which to study nucleic acid from diverse sources. Metagenomic clone libraries in particular have aided in studies of microbial biodiversity and function, as well as allowed the mining of novel enzymes for specific functions of interest. These libraries are often constructed by cloning large-inserts (∼30 kb) in...

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Literature Corpus work: dd3a5883-1765-5532-af84-b17dda2a634c
DOI: 10.1101/013763

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