Article

Promoter activity of ORF-less gene cassettes isolated from the oral metagenome

2018-09-27

Abstract excerpt

Integrons are genetic elements consisting of a functional platform for recombination and expression of gene cassettes (GCs). GCs usually carry promoter-less open reading frames (ORFs), encoding proteins with various functions including antibiotic resistance. The transcription of GCs relies mainly on a cassette promoter (P C ), located upstream of an array of GCs. Some integron GCs, called ORF-less GCs, contain no...

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Literature Corpus work: 0624af56-0ecd-5c67-911c-32d0f90c5106
DOI: 10.1101/427781

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