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Article

Genome-wide dysregulation of histone acetylation in the Parkinson’s disease brain

2019-09-28

Abstract excerpt

Parkinson disease (PD) is a complex neurodegenerative disorder of largely unknown etiology. While several genetic risk factors have been identified, the involvement of epigenetics in the pathophysiology of PD is mostly unaccounted for. We conducted a histone acetylome-wide association study in PD, using brain tissue from two independent cohorts of cases and controls. Immunoblotting revealed increased acetylation a...

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Literature Corpus work
dcf97174-c594-512b-a466-dde163dce1f4
DOI
10.1101/785550
Open publication

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Genome-wide dysregulation of histone acetylation in the Parkinson’s disease brainDOI 10.1101/785550
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