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Entanglement of Genetics and Epigenetics in Parkinson’s Disease

29 Mar 2019

Abstract excerpt

Parkinson disease (PD) is a common neurodegenerative disorder that progresses with age, with an increasing number of symptoms. Some of the efforts to understand PD progression have been focusing on the regulation of epigenetic mechanisms, that generally include small molecular modifications to the DNA and histones that are essential for regulating gene activity. Here, we have pointed out difficulties to untangle...

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PMID: 30983962
DOI: 10.3389/fnins.2019.00277

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