Article
Epigenetic regulation in Parkinson's disease.
Acta neuropathologica - 1 Oct 2016
Labbé Catherine, Lorenzo-Betancor Oswaldo, Ross Owen A
Abstract excerpt
Recent efforts have shed new light on the epigenetic mechanisms driving gene expression alterations associated with Parkinson's disease (PD) pathogenesis. Changes in gene expression are a well-established cause of PD, and epigenetic mechanisms likely play a pivotal role in regulation. Studies in families with PD harboring duplications and triplications of the SNCA gene have demonstrated that gene dosage is...
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