Article

90K/<i>LGALS3BP</i> Expression is Upregulated in COVID-19 but Does Not Restrict SARS-CoV-2 Infection

2022-07-19

Abstract excerpt

Glycoprotein 90K, encoded by the interferon-stimulated gene LGALS3BP , displays broad antiviral activity. It reduces HIV-1 infectivity by interfering with Env maturation and virion incorporation, and increases survival of Influenza A virus-infected mice via antiviral innate immune signaling. Here, we analyzed the expression of 90K/ LGALS3BP in 44 hospitalized COVID-19 patients. 90K protein serum levels were signif...

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Literature Corpus work: dcc5cd6f-560a-58a0-882e-507963916c41
DOI: 10.1101/2022.07.18.22277255

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