Article

Surfaceome CRISPR Screen Identifies OLFML3 as a Rhinovirus-inducible IFN Antagonist

2020-11-08

Abstract excerpt

<h4>Background</h4> Rhinoviruses (RVs) cause more than half of common cold and, in some cases, more severe diseases. Functional genomics analyses of RVs using siRNA or genome-wide CRISPR screen uncovered a limited set of host factors, few of which has proven clinical relevance. <h4>Results</h4> Herein, we systematically compared genome-wide CRISPR screen and surface protein-focused CRISPR screen, referred to as...

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Literature Corpus work: c0b3f98d-9fe8-5119-a979-6dd2af326a2b
DOI: 10.1101/2020.11.08.372607

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