Article

ANDROMEDA by Prosilico Software Successfully Predicts Human Clinical Pharmacokinetics of 300 Drugs Out of Reach for <i>In Vitro</i> Methods

2022-10-07

Abstract excerpt

<h4> A bstract </h4> <h4>Introduction</h4> In vitro measurements and predictions of human clinical pharmacokinetics (PK) are sometimes hindered and made impossible due to factors such as extensive binding to materials, low methodological sensitivity and large variability. <h4>Methods</h4> The objective was to find compounds out of reach for in vitro PK-methods and (if possible) predict corresponding human c...

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Literature Corpus work: dcc04fea-f7d1-53f3-bac7-d1dd521cadd9
DOI: 10.1101/2022.10.05.511015

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