Article

A New Approach for In Silico Prediction of Oral Drug Concentration Profiles in Human for Drug Candidates Lack Experimental Pharmacokinetic Data

2021-07-09

Abstract excerpt

<title>Abstract</title> The purpose of this study is to develop a novel protocol to preliminarily predict the concentration profiles of a target drug based on the PBPK model of a structurally similar template drug by combining two software for PBPK modeling, the SimCYP simulator and ADMET Predictor.<bold> </bold>The method was evaluated by utilizing 13 drug pairs which come from 18 drugs in the built-in databa...

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Literature Corpus work: 195d6959-015c-5084-a942-9f61125fe4be
DOI: 10.21203/rs.3.rs-687537/v1

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