Article
The prognostic role of p53 mutations in metastatic colorectal cancer: A systematic review and meta-analysis.
Critical reviews in oncology/hematology - 1 Jun 2023
Ottaiano Alessandro, Santorsola Mariachiara, Capuozzo Maurizio, Perri Francesco, Circelli Luisa, Cascella Marco, Ianniello Monica, Sabbatino Francesco, Granata Vincenza, Izzo Francesco, Iervolino Domenico, Casillo Marika, Petrillo Nadia, Gualillo Oreste, Nasti Guglielmo, Savarese Giovanni
Abstract excerpt
INTRODUCTION: P53 is one of the most frequently mutated genes in colorectal cancer (CRC). The present study was undertaken to provide a solid estimate of the prognostic value of p53 mutations in metastatic CRC patients. METHODS: This meta-analysis was done in accordance to the Preferred Reporting Item For Systematic Reviews and Meta-Analysis 2020 guidelines. Studies in English published in the last ten years were...
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