Article

A Novel Xenonucleic Acid Mediated Molecular Clamping Technology for Early Colorectal Cancer Screening

2020-05-16

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Colorectal cancer (CRC) is one of the leading causes of cancer-related death. Early detection is critical to reduce CRC morbidity and mortality. In order to meet this need, we developed a molecular clamping assay called the ColoScape ™ for early colorectal cancer diagnostics. <h4>Methods</h4> Nineteen mutations in four genes APC, KRAS, BRAF and CTNNB1 associated with early...

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Literature Corpus work: dc9929de-5613-5ca2-b2af-f8638d81d989
DOI: 10.1101/2020.05.15.098954

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