Detecting known neoepitopes, gene fusions, transposable elements, and circular RNAs in cell-free RNA

Abstract excerpt

<h4>ABSTRACT</h4> Cancer is the second leading cause of death worldwide, and although there have been advances in treatments, including immunotherapies, these often require biopsies which can be costly and invasive to obtain. Due to lack of pre-emptive cancer detection methods, many cases of cancer are detected at a late stage when the definitive symptoms appear. Plasma samples are relatively easy to obtain, and t...

Topics

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• Cancer Genomics and Diagnostics
• Cell-Free Nucleic Acids
• Chromatin Assembly and Disassembly
• Chromatin Immunoprecipitation
• Clinical Decision-Making
• Early Detection of Cancer
• Mutation
• Neoplasms

Identifiers and source

Literature Corpus work

187ed967-6f2c-5e96-9e81-8697f65af3c4

DOI

10.1101/2024.06.07.24308622