Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Circulating tumor DNA-based early detection of precancerous colorectal lesions using QClamp XNA-mediated real-time PCR.

Die Pharmazie - 5 Dec 2021

Chen Shuo, Wang Yan, Wang Kai, Zhang Lin, Zhang Xipeng

Abstract excerpt

The mutation status of the gene involved in early colorectal carcinogenesis and micro-invasive liquid biopsy allows detection of mutated circulating tumor DNA (ctDNA). Early detection of precancerous lesions and CRC is vital in proper treatment and hence associated to patient survival. The frequency of APC, CTNNB1, KRAS, and BRAF mutations in circulating free DNA (cfDNA) were analyzed to evaluate the performance...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenoma
Share to Cell-Free Nucleic Acids
Share to Circulating Tumor DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Precancerous Conditions

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins p21(ras)

Share to Real-Time Polymerase Chain Reaction

Source

Identifiers

PMID: 34986957
DOI: 10.1691/ph.2021.1780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Circulating tumor DNA-based early detection of precancerous colorectal lesions using QClamp XNA-mediated real-time PCR.PMID 34986957Read ↗

A novel xenonucleic acid-mediated molecular clamping technology for early colorectal cancer screening.Semantic proximity Read ↗

A Novel Xenonucleic Acid Mediated Molecular Clamping Technology for Early Colorectal Cancer ScreeningSemantic proximity Read ↗

A Novel Xenonucleic Acid Mediated Molecular Clamping Technology for Early Colorectal Cancer ScreeningSemantic proximity Read ↗

Circulating tumor DNA detectable in early- and late-stage colorectal cancer patients.Semantic proximity Read ↗

Circulating free DNA in a screening program for early colorectal cancer detection.Semantic proximity Read ↗

Discovery and validation of methylation signatures in blood-based circulating tumor cell-free DNA in early detection of colorectal carcinoma: a case–control studySemantic proximity Read ↗

Plasma mutation profile of precursor lesions and colorectal cancer using the Oncomine Colon cfDNA Assay.Semantic proximity Read ↗

Circulating cell-free nucleic acids as biomarkers in colorectal cancer screening and diagnosis - an updateSemantic proximity Read ↗

Plasma mutation profile of precursor lesions and colorectal cancer using the Oncomine Colon cfDNA AssaySemantic proximity Read ↗

Circulating cell-free nucleic acids as biomarkers in colorectal cancer screening and diagnosis.Semantic proximity Read ↗

Circulating lncRNAs as Early Diagnostic Biomarkers for Colorectal Cancer: A case-control diagnostic accuracy studySemantic proximity Read ↗

Tumor-associated DNA mutation detection in individuals undergoing colonoscopy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.