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Plasma mutation profile of precursor lesions and colorectal cancer using the Oncomine Colon cfDNA Assay.

BMC cancer - 18 Dec 2024

Dos Reis Mariana Bisarro, Dos Santos Wellington, de Carvalho Ana Carolina, Lima Adhara Brandão, Reis Monise Tadin, Santos Florinda, Reis Rui Manuel, Guimarães Denise Peixoto

Abstract excerpt

BACKGROUND: Colorectal cancer (CRC) is the second leading cause of cancer death worldwide. Early detection of precursor lesions or early-stage cancer could hamper cancer development or improve survival rates. Liquid biopsy, which detects tumor biomarkers, such as mutations, in blood, is a promising avenue for cancer screening. AIM: To assess the presence of genetic variants in plasma cell-free tumor DNA from...

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Identifiers

PMID: 39695441
DOI: 10.1186/s12885-024-13287-2
PMCID: PMC11657448

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