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Article

Treatment monitoring of colorectal cancer by integrated analysis of plasma concentration and sequencing of circulating tumor DNA.

Molecular cancer - 26 Oct 2020

Yeh Yu-Min, Lin Peng-Chan, Lee Chung-Ta, Chen Shang-Hung, Lin Bo-Wen, Lin Shao-Chieh, Chen Po-Chuan, Chan Ren-Hao, Shen Meng-Ru

Abstract excerpt

Circulating cell-free DNA (cfDNA) analysis is an important tool for cancer monitoring. The patient-specific mutations identified in colorectal cancer (CRC) tissues are usually used to design the cfDNA analysis. Despite high specificity in predicting relapse, the sensitivity in most studies is around 40-50%. To improve this weakness, we designed a cfDNA panel according to the CRC genomic landscape and...

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Identifiers

PMID: 33106181
DOI: 10.1186/s12943-020-01273-8
PMCID: PMC7586655

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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