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The expression level of CACNA1C-encoded Ca <sub>V</sub> 1.2 is a tipping point between promotion and inhibition of dendritic growth in neurons

2025-12-13

Abstract excerpt

<h4>ABSTRACT</h4> The CACNA1C gene encodes the Ca V 1.2 L-type voltage-gated calcium channel, which plays a crucial role in neuronal signaling. CACNA1C is a risk gene for psychiatric conditions involving disruption of neuronal connectivity such as schizophrenia, autism, and bipolar disorders. While genomic studies are consistently reinforcing the notion of CACNA1C as an important locus related to these diseases,...

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Literature Corpus work
dc89153d-a883-5f70-9447-0b76961c7534
DOI
10.64898/2025.12.11.693636
Open publication

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