Article

Bipolar-associated miR-499-5p controls neuroplasticity by downregulating the Ca <sub>v</sub> 1.2 L-type voltage gated calcium channel subunit CACNB2

2021-06-10

Abstract excerpt

<h4>ABSTRACT</h4> Bipolar disorder (BD) is a chronic mood disorder characterized by alternating manic and depressive episodes, often in conjunction with cognitive deficits. Dysregulation of neuroplasticity and calcium homeostasis as a result of complex genetic environment interactions are frequently observed in BD patients, but the underlying molecular mechanisms are largely unknown. Here, we show that a BD-assoc...

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Literature Corpus work: d1ecf57a-3c41-5d13-975a-0bd54e5764ce
DOI: 10.1101/2021.06.09.447782

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