Article

Compartment-specific tuning of hippocampal dendritic feature selectivity by intracellular Ca <sup>2+</sup> release

2021-09-28

Abstract excerpt

Dendritic Ca 2+ signaling is central to neural plasticity mechanisms allowing animals to adapt to the environment. Intracellular Ca 2+ release (ICR) from endoplasmic reticulum has long been thought to shape these mechanisms. However, ICR has not been investigated in mammalian neurons in vivo . We combined electroporation of single CA1 pyramidal neurons, simultaneous imaging of dendritic and somatic activity dur...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 5f92574e-c754-53dd-a0a7-6b203e843126
DOI: 10.1101/2021.09.27.460811

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Compartment-specific tuning of hippocampal dendritic feature selectivity by intracellular Ca <sup>2+</sup> releaseDOI 10.1101/2021.09.27.460811Read

Dendritic structural degeneration is functionally linked to cellular hyperexcitability in a mouse model of Alzheimer's disease.Semantic proximity Read

<i>DendroTweaks</i> : An interactive approach for unraveling dendritic dynamicsSemantic proximity Read

The expression level of CACNA1C-encoded Ca <sub>V</sub> 1.2 is a tipping point between promotion and inhibition of dendritic growth in neuronsSemantic proximity Read

Somatic Depolarization Enhances Hippocampal CA1 Dendritic Spike Propagation and Distal Input Driven Synaptic PlasticitySemantic proximity Read

Clustered Inputs Maximize Efficiency for Stable Place Field Encoding in Hippocampal Pyramidal NeuronsSemantic proximity Read

A Minimal Biophysical Model of Neocortical Pyramidal Cells: Implications for Frontal Cortex Microcircuitry and Field Potential GenerationSemantic proximity Read

How to train your neuron: Developing a detailed, up-to-date, multipurpose model of hippocampal CA1 pyramidal cellsSemantic proximity Read

Deficits in neuronal architecture but not over-inhibition are main determinants of reduced neuronal network activity in a mouse model of overexpression of <i>Dyrk1A</i>Semantic proximity Read

Distinct nanoscale architectures of GABAergic inhibitory synapses predict diverse synaptic outputSemantic proximity Read

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill RatesSemantic proximity Read

Regulation of neuronal input transformations by tunable dendritic inhibition.Semantic proximity Read

Norepinephrine regulates Ca <sup>2+</sup> signals and fate of oligodendrocyte progenitor cells in the cortexSemantic proximity Read