Article

The impact on clinical success from the 23andMe cohort

2024-06-18

Abstract excerpt

90% of therapeutic programs that enter clinical trials ultimately fail. Human genetic variation provides a set of “natural experiments” that can inform successful strategies for therapeutic discovery. Previous work has estimated that drug targets with human genetics supported mechanisms have a 2-3x increased likelihood of succeeding in the clinic compared to those without. 23andMe, Inc. is a direct-to-consumer gen...

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Literature Corpus work: dc269208-a19c-5082-9153-6565abb84427
DOI: 10.1101/2024.06.17.24309059

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